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IMR5 cells) largely abrogates AURORA-AT217D depletion
DC_C66 has a good selectivity for CARM1 against PRMT1 (IC50=21 μM)
BML-284 induces TCF-dependent transcriptional activity with an EC50 of 700 nM
4-tetrahydroisoquinolin-2-yl}-5-(3-{4-[3-(dimethylamino)prop-1-yn-1-yl]-2-fluorophenoxy}propyl)-1
18E)-6-hydroxy-3
(S)-AM-5308 Catalog No.:M33718-C IMR5 cells) largely abrogates AURORA-AT217D(S) AM 5308 (compound 7 13) is a potent kinesin KIF18A inhibitor with an IC50 of 46 nM for KIF18A ATPase. (S) AM 5308 has the potential for cancer research Product information CAS Number: 2446340 45 8 Molecular Weight: 529. 65 Formula: C26H35N5O5S Smiles: C[C@H]1CN(CCO1)C1=CC=CC(NC(=O)C2=CC=C(C=C2N2CCC3(CC2)CC3)NS(=O)(=O)CCO)=N1 InChiKey: IUDCFCQNVQWCCI IBGZPJMESA N InChi: InChI=1S C26H35N5O5S c1 19 18 31(13 15 36 19)24 4 2 3 23(27 24)28 25(33)21 6 5
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