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Sphingosine-1-phosphate (S1P) is an extracellular lipid mediator released by activated blood platelets that serves to influence heart rate
22)29-19)14-3-4-20(26)28-13-14/h3-4
4 µM and a Kd of 0
3)4)65-51(68)33-73-23-22-71-20-21-72-24-25-74-45-16-12-39(13-17-45)41-14-18-48-46(27-41)54(62-34-61-48)64-43-15-19-50(47(58)28-43)75-32-38-6-5-7-42(59)26-38/h5-19
InChiKey: LBPKYPYHDKKRFS-UHFFFAOYSA-N
Koumine 18847 Sphingosine-1-phosphate (S1P) is an extracellularKoumine is an alkaloid separated from Gelsemium elegans, shows potent anti tumor activity. Koumine up regulates the Bax Bcl 2 ratio and caspase 3 expression in human breast cancer cells. Koumine has anxiolytic, antistress, antipsoriatic, and analgesic activities, protects against the development of arthritis in Rheumatoid arthritis (RA) animal models. Product information CAS Number: 1358 76 5 Molecular Weight: 306. 40 Formula: C20H22N2O Chemical Name:
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