D-α-Hydroxyglutaric acid odesine Smiles: COC1C=C2C(=CNC2=CC=1)C1CCNCC=1

Smiles: COC1C=C2C(=CNC2=CC=1)C1CCNCC=1

5S)-2-[(1S)-1-[(3S

Smiles: CC1C=C(C(=CC=1)N1N=CC=N1)C(=O)N1CCN(CC[C@H]1C)C1=NC2=CC(Cl)=CC=C2O1

3-dihydro-1H-inden- 1-yl]-1

Bucladesine sodium is a cardiac stimulant

D-α-Hydroxyglutaric acid odesine Smiles: COC1C=C2C(=CNC2=CC=1)C1CCNCC=1D Hydroxyglutaric acid ((R) 2 Hydroxyglutarate) is the principal metabolite accumulating in neurometabolic disease D 2 hydroxyglutaric aciduria. D Hydroxyglutaric acid is a weak competitive antagonist of ketoglutarate ( KG) and inhibits multiple KG dependent dioxygenases with a Ki of 10. 87 mM. D Hydroxyglutaric acid increases reactive oxygen species (ROS) production. D Hydroxyglutaric acid binds and inhibits ATP synthase and inhibits mTOR signaling.