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InChi: InChI=1S/C27H38N4O7S/c1-17(2)14-23(27(35)36)29-26(34)18-4-7-21(8-5-18)31-12-10-20(11-13-31)28-16-25(33)19-6-9-24(32)22(15-19)30-39(3
CAS Number: 5042-09-1
2014 Nov 4
InChiKey: MAYJEFRPIKEYBL-OASIGRBWSA-N
the tumors of the animals treated with 10 mpk drug dosage start to grow again
H3B-5942 )-(+)-Rolipram InChi: InChI=1S/C27H38N4O7S/c1-17(2)14-23(27(35)36)29-26(34)18-4-7-21(8-5-18)31-12-10-20(11-13-31)28-16-25(33)19-6-9-24(32)22(15-19)30-39(3H3B 5942 is a selective, irreversible and orally active estrogen receptor covalent antagonist, inactivates both wild type and mutant ER by targeting Cys530, with Kis of 1 nM and 0. 41 nM, respectively. H3B 5942 reduces ER target gene GREB1, shows potent antitumor activity both in multiple cell lines or animals bearing ERWT or ER mutations. Product information CAS Number: 2052128 15 9 Molecular Weight: 494. 63 Formula: C31H34N4O2 Chemical Name: (2E) 4