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Inhibition of TNF-alpha
Gimeracil enhances the antitumor activity of fluoropyrimidines by competitively and reversibly inhibiting the enzyme dihydropyrimidine dehydrogenase causing decreased degradation of the fluoropyrimidines
PLX647 dihydrochloride shows selectivity for FMS and KIT over a panel of 400 kinases at a concentration of 1 μM except FLT3 and KDR (IC50s=91 and 130 nM
InChi: InChI=1S/C17H21N7O4/c25-24(26)14-3-1-13(2-4-14)18-15-19-16(22-5-9-27-10-6-22)21-17(20-15)23-7-11-28-12-8-23/h1-4H
27(35)36)28(37)38/h14
1, 2, 3, 4-Tetrahydro-β-carboline-1-carboxylic acid oside Re Inhibition of TNF-alpha1,2,3,4 Tetrahydro carboline 1 carboxylic acid is a chemical used on the study of neurodegenerative diseases. Product information CAS Number: 6649 91 8 Molecular Weight: 216. 24 Formula: C12H12N2O2 Chemical Name: 1H,2H,3H,4H,9H pyrido[3,4 b]indole 1 carboxylic acid Smiles: OC(=O)C1NCCC2C3C=CC=CC=3NC=21 InChiKey: XGCIVVYTCDKDLC UHFFFAOYSA N InChi: InChI=1S C12H12N2O2 c15 12(16)11 10 8(5 6 13 11)7 3 1 2 4 9(7)14 10 h1 4,11,13 14H,5 6H2,(H,15,16)
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