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The IC50 values for 11-hydroxylase and CYP3A4 are above 1μM and above 10μM
46)9/h12-15
InChi: InChI=1S/C25H28ClN3O2/c1-27(2)13-14-29-16-21(20-8-7-19(26)15-23(20)29)24(30)28-11-9-25(10-12-28)22-6-4-3-5-18(22)17-31-25/h3-8
SAR260301 also leads to antitumor activities in PTEN-deficient/BRAF-mutant human melanoma cells
6-24 hours
PF 184 saconazole-D5 The IC50 values for 11-hydroxylaseProduct information CAS Number: 1187460 81 6 Molecular Weight: 619. 09 Formula: C32H32ClFN6O4 Chemical Name: 2 [(3S,4S) 3,4 bis(hydroxymethyl) 3,4 dimethylpyrrolidin 1 yl] N [3 carbamoyl 1 (4 fluorophenyl) 1H,4H,5H benzo[g]indazol 8 yl] 5 chloropyridine 4 carboxamide Smiles: C[C@]1(CN(C[C@@]1(C)CO)C1C=C(C(Cl)=CN=1)C(=O)NC1C=C2C3=C(CCC2=CC=1)C(=NN3C1C=CC(F)=CC=1)C(N)=O)CO InChiKey: JUOWWGNRWRLBSV ACHIHNKUSA N InChi: InChI=1S C32H32ClFN6O4 c1 31(16
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