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CAS Number: 1404562-17-9
it is against Colorectal cancer cell lines growth with IC50 values ranging from 11
100 and 220 nM for human D2
with 50 nM PU-H71 needed to significantly reduce the LPS dependent nitrite release
Smiles: CN1CCN(CC2=CC=C(C=C2)C(=O)NC2C=C(NC3=NC(=CS3)C3=CC=CN=C3)C(C)=CC=2)CC1
(S)-Lisofylline Catalog No.:M22422-C CAS Number: 1404562-17-9Lisofylline (LSF) is a potent anti inflammatory agent. LSF is a chiral metabolite of pentoxifylline . Pentoxifylline is exclusively reduced to (S) LSF in the cytosol when metabolized by isolated human liver cells . In vitro: Lisofylline preserved cell insulin secretion and inhibited DNA damage of islets in the presence of IL 1 . Simultaneous application of LSF and cytokines to INS 1 cells restored insulin secretion, mitochondrial membrane potential,