YAP-TEAD-IN-1 TFA 64 Racemate Smiles: COC1=CC=C(C=C1OC1CCCC1)[C@H]1CC(=O)NC1

Smiles: COC1=CC=C(C=C1OC1CCCC1)[C@H]1CC(=O)NC1

Dyatkina N

InChi: InChI=1S/C20H17FN6O/c1-12-13(3-2-7-22-12)16-10-24-20(27-11-25-26-19(16)27)23-9-15-14-6-8-28-18(14)5-4-17(15)21/h2-5

JZL184 is highly selective

2S)-2-[(3S

YAP-TEAD-IN-1 TFA 64 Racemate Smiles: COC1=CC=C(C=C1OC1CCCC1)[C@H]1CC(=O)NC1YAP TEAD IN 1 TFA is a potent and competitive peptide inhibitor of YAP TEAD interaction (IC50=25 nM). YAP TEAD IN 1 TFA is a 17mer peptide and shows a higher the binding affinity to TEAD1 (Kd=15 nM) than YAP (50 171) (Kd= 40 nM). Product information CAS Number: 1659305 79 9 Molecular Weight: 2133. 89 Formula: C95H145ClF3N23O23S2 Chemical Name: (4S) 4 ((2S) 1 ((2S) 1 ((2S) 2 ((3S, 6S, 9S, 18S, 21S, 24S, 27S, 30S, 35aS) 18 ((S) 2 ((S) 1 ((S) 2 acetamido