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JW67 (1 μM
Smiles: C[C@@]12CC[C@]3(CC[C@@H](C)[C@H](C)[C@H]3C1=CC[C@H]1[C@@]2(C)CC[C@H]2[C@](C)(CO)[C@@H](O)[C@H](O)C[C@@]21C)C(=O)O[C@@H]1O[C@H](CO[C@@H]2O[C@H](CO)[C@@H](O[C@@H]3O[C@@H](C)[C@H](O)[C@@H](O)[C@H]3O)[C@H](O)[C@H]2O)[C@@H](O)[C@H](O)[C@H]1O
11-pentaen-3-yl}ethyl)-N-{2-[2-(2-{[2-(2
Inhibiting an immediate TCR signal has promise for treating a broad spectrum of human T cell-mediated autoimmune and inflammatory diseases
7R)-7-amino-3-chloro-8-oxo-5-thia-1-azabicyclo[4
Nintedanib D3 VZ 185 JW67 (1 μMProduct information CAS Number: 1624587 84 3 Molecular Weight: 542. 64 Formula: C31H33N5O4 Chemical Name: methyl 2 hydroxy 3 {[(4 {N methyl 2 [4 (H)methylpiperazin 1 yl]acetamido}phenyl)imino](phenyl)methyl} 1H indole 6 carboxylate Smiles: [2H]C([2H])([2H])N1CCN(CC(=O)N(C)C2C=CC(=CC=2)N=C(C2=C(O)NC3=CC(=CC=C32)C(=O)OC)C2C=CC=CC=2)CC1 InChiKey: CPMDPSXJELVGJG OTNMTZDTSA N InChi: InChI=1S C31H33N5O4 c1 34 15 17 36(18 16 34)20 27(37)35(2)24 12 10 23(11
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