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UK122 Catalog No.:M14474-2 Smiles: CC1SC2=C(C(=N[C@@H](CC(=O)NCCOCCOCCOCC(=O)N[C@H](C(=O)N3C[C@H](O)C[C@H]3C(=O)NCC3C=CC(=CC=3)C3SC=NC=3C)C(C)(C)C)C3=NN=C(C)N23)C2C=CC(Cl)=CC=2)C=1C

SKU: 37934144890

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Description

Smiles: CC1SC2=C(C(=N[C@@H](CC(=O)NCCOCCOCCOCC(=O)N[C@H](C(=O)N3C[C@H](O)C[C@H]3C(=O)NCC3C=CC(=CC=3)C3SC=NC=3C)C(C)(C)C)C3=NN=C(C)N23)C2C=CC(Cl)=CC=2)C=1C

preventing dopaminergic cell death in the striatum and improving motor function

WO2017212012A1

2010 Apr 30

InChi: InChI=1S/C26H30N6O3/c1-26(2

UK122 Catalog No.:M14474-2 Smiles: CC1SC2=C(C(=N[C@@H](CC(=O)NCCOCCOCCOCC(=O)N[C@H](C(=O)N3C[C@H](O)C[C@H]3C(=O)NCC3C=CC(=CC=3)C3SC=NC=3C)C(C)(C)C)C3=NN=C(C)N23)C2C=CC(Cl)=CC=2)C=1CUK122 is a potent and selective urokinase type plasminogen activator (uPA) inhibitor with an IC50 of 0. 2 M. UK122 shows no or little inhibition of tissue type PA (tPA), plasmin, thrombin, and trypsin (all IC50>100 M). UK122, 4 oxazolidinone analogue, is an anticancer agent and inhibits cancer cell migration and invasion. Product information CAS Number: 940290 58 4 Molecular Weight: 291. 30 Formula: C17H13N3O2 Chemical Name: 4 {[(4E) 5 oxo 2 phenyl

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